Search
Close this search box.

OMF Announces New “Brain Fog” Study

Inside the lab at the Collaborative Research Center at Uppsala University, Sweden

About the Study

Open Medicine Foundation (OMF) is excited to announce a new collaborative study between the ME / CFS Collaborative Research Center at Uppsala, Sweden and the Harvard ME / CFS Collaboration.

This study focuses on biomarkers for long-term neurocognitive outcomes. It provides an excellent opportunity to understand the mechanism of long-lasting viral-induced cognitive complications, commonly referred to as “brain fog.” Brain fog is one of the significant symptoms of those suffering from Myalgic Encephalomyelitis/chronic fatigue syndrome (ME / CFS) and is also seen in patients with herpes simplex encephalitis (HSE).

Objectives:

Investigate the correlation between biomarkers for brain inflammation and long-term neurocognitive outcomes in patients with herpes simplex encephalitis (HSE).

Method:

Fifty patients with Herpes Simplex Encephalitis (HSE) had blood and cerebrospinal fluid (CSF) sampled at three separate intervals – while in ICU, two weeks later and three months later. During these three months, all 50 patients appear to suffer from post-viral fatigue syndrome (PVFS), and many are expected to qualify for ME / CFS diagnosis at six months.

Markers of neuroinflammation will be measured in the CSF, while markers of altered metabolism will be identified in the blood. These markers will be correlated to symptom expression. A panel of markers from each time point will be used to biologically distinguish those that develop ME / CFS from those that do not.

Conclusions:

Our findings could give predictive evidence of long term neurocognitive outcomes in HSE and suggest a causative chain of events where brain tissue damage increases the risk of subsequent prolongation of CSF inflammation and post-viral fatigue. The data could guide a future intervention study of immunosuppressive therapy administered in the recovery phase of HSE and other viral infections with neurological sequelae.

This study reveals why OMF uses the word “Collaborative” to describe the research that we fund! Our guiding philosophy is that a collaborative approach accelerates research.

In the words of OMF founder and CEO Linda Tannenbaum:

“We are delighted to fund this important project, which allows for collaboration between the Uppsala and Harvard Collaborative Research Centers.

We want to thank our OMF family, whose support and advocacy make our research possible.”

 


OMF is a Proud Sponsor of the
IACFS/ME 2020 Virtual Conference 

The International Association for Chronic Fatigue Syndrome / Myalgic Encephalomyelitis (IACFS/ME) has announced its first virtual research conference to be held on August 21, 2020 at 10am EDT.

The conference will focus on biomedical, public health, and behavioral aspects of ME / CFS and associated comorbidities. OMF’s Chief Medical Officer, Dr. Ronald Tompkins, will be speaking on the conversion of COVID-19 patients to people with ME / CFS.

A portion of the meeting will also be devoted to COVID-19 and its relevance to ME / CFS research and clinical care.

 View the full conference schedule

 Learn more or register today

If you are able, please consider contributing to our effort to uncover research-based answers.

Help us improve the quality of life for all sufferers of ME / CFS and other chronic complex diseases, such as Post Treatment Lyme Disease Syndrome and Fibromyalgia.



Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation®

What are the advantages of giving from your Donor Advised Fund (DAF)?

  • Your gifts to your donor advised fund entitle you to an immediate income tax deduction at the time of contribution.
  • You avoid capital gains tax on appreciated assets you place in your donor advised fund.
  • Your fund’s investment gains accumulate tax free.
  • Funds are distributed to Open Medicine Foundation in your name and immediately put to use to support our worldwide research efforts.


How do I make a donation through my DAF?

Just click on the DAF widget below. It is simple and convenient to find your fund among the over 900 funds in our system.

Still can’t find your fund? 

  • Request a grant distribution through your Donor Advised Fund sponsor
  • Be sure to use OMF’s EIN #26-4712664
  • You can also designate OMF as a beneficiary for your Donor Advised Fund
  • Questions? Give us a call at 650-242-8669